Troponins in cardiac amyloidosis: multipurpose markers

Cardiac troponins.

Cardiac troponins

Objective: To review the use of cardiac troponins as biomarkers for myocardial injury in human and veterinary medicine. Data sources: Data sources included scientific reviews and original research publications. Human data synthesis: Cardiac troponins have been extensively studied in human medicine. Finding an elevated cardiac troponin level carries important diagnostic and prognostic informatio...

Are cardiac troponins reliable serodiagnositic markers of cardiac ischaemia in end-stage renal disease?

RRT irrespective of the primary renal diagnosis and of the apparent duration of the diabetic disease. Conclusions Available data suggest that a proportion of RRT patients develop diabetes after renal treatment is started. The pathogenesis of the disease is multifactor-ial. In any case diabetes has a strong impact on survival. I hope that this editorial comment may motivate other nephrologists t...

Cardiac troponins in intensive care

The cardiac troponins are integral components of the myofibrillary apparatus and they regulate muscle contraction. The measurement of cardiac troponins has replaced other biomarkers for the specific detection of myocardial necrosis and for the diagnosis of myocardial infarction. The tissue specificity plus sensitivity of the measurement technology has meant that cardiac damage can be detected i...

Circulating Cardiac Troponins in Small Animals

INTRODUCTION The cardiac troponins I, T, and C (cTnI, cTnT, and cTnC) are thin filament-associated regulatory proteins of the heart muscle. They are crucial to the interaction between actin and myosin and occur at regular intervals of 38 nm along the tropomyosin molecule. Cardiac troponin I ("I" for inhibition) is uniquely expressed in the myocardium and is a potent inhibitor of the process of ...